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Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis / Van Kerkhove MD in PLoS medicine [PLoS Med], Vol. 8, N° 7 ([01/07/2011])  

[article]  inPLoS medicine [PLoS Med] > Vol. 8, N° 7 [01/07/2011] . - e1001053 Titre : Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis Type de document : Article scientifique Auteur(s) : Van Kerkhove MD ; Vandemaele KA ; Shinde V ; Jaramillo Gutierrez G ; Koukounari A ; Donnelly CA ; Carlino LO ; Owen R ; Paterson B ; Pelletier L ; Vachon J ; Gonzalez C ; Hongjie Y ; Zijian F ; Chuang SK ; Au A ; Buda S ; Krause G ; Haas W ; Bonmarin I ; Taniguichi K ; Nakajima K ; Shobayashi T ; Takayama Y ; Sunagawa T ; Heraud JM ; Orelle A ; Palacios E ; van der Sande MA ; Wielders CC ; Hunt D ; Cutter J ; Thomas J ; Santa Olalla P ; Sierra Moros MJ ; Hanshaoworakul W ; Ungchusak K ; Pebody R ; Jain S ; Mounts AW ; WHO Working Group for Risk Factors for Severe H1N1pdm Infection Appartenance auteur(s) InVS DMI Année de publication : 2011 Article en page(s) : e1001053 Langues : Anglais (eng) Mots-clés : Nouvelle grippe A (H1N1) ; Pandémie ; Population exposée risque Résumé : BACKGROUND: Since the start of the 2009 influenza A pandemic (H1N1pdm), the World Health Organization and its member states have gathered information to characterize the clinical severity of H1N1pdm infection and to assist policy makers to determine risk groups for targeted control measures. METHODS AND FINDINGS: Data were collected on approximately 70,000 laboratory-confirmed hospitalized H1N1pdm patients, 9,700 patients admitted to intensive care units (ICUs), and 2,500 deaths reported between 1 April 2009 and 1 January 2010 from 19 countries or administrative regions--Argentina, Australia, Canada, Chile, China, France, Germany, Hong Kong SAR, Japan, Madagascar, Mexico, The Netherlands, New Zealand, Singapore, South Africa, Spain, Thailand, the United States, and the United Kingdom--to characterize and compare the distribution of risk factors among H1N1pdm patients at three levels of severity: hospitalizations, ICU admissions, and deaths. The median age of patients increased with severity of disease. The highest per capita risk of hospitalization was among patients CONCLUSIONS: Our results demonstrate that risk factors for severe H1N1pdm infection are similar to those for seasonal influenza, with some notable differences, such as younger age groups and obesity, and reinforce the need to identify and protect groups at highest risk of severe outcomes. Please see later in the article for the Editors' Summary. (R.A.) PMID Pubmed : Pubmed : 21750667 Lien externe DOI : DOI : 10.1371/journal.pmed.1001053 Corpus : Grippe A(H1N1)/Production scientifique InVS Lien(s) externe(s) : http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001053 Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=9764 [article]

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