Documents disponibles écrits par cet auteur

Acute effects of ozone on mortality from the "air pollution and health: a European approach" project / Gryparis A in American Journal of Respiratory and Critical Care Medicine [Am J Respir Crit Care Med], Vol. 170, N° 10 (11/2004)

[article]  inAmerican Journal of Respiratory and Critical Care Medicine [Am J Respir Crit Care Med] > Vol. 170, N° 10 (11/2004) . - 1080-7 Titre : Acute effects of ozone on mortality from the "air pollution and health: a European approach" project Type de document : Article scientifique Auteur(s) : Gryparis A ; Forsberg B ; Katsouyanni K ; Analitis A ; Touloumi G ; Schwartz J ; Samoli E ; Medina S ; Anderson HR ; Niciu EM ; Wichmann HE ; Kriz B ; Kosnik M ; Skorkovsky J ; Vonk J ; Dortbudak Z Appartenance auteur(s) InVS DSE Année de publication : 2004 Article en page(s) : 1080-7 Langues : Anglais (eng) Mots-clés : Pollution atmosphérique ; Milieu urbain ; Ozone ; Mortalité ; Cause décès ; Etude comparée ; Europe ; Risque relatif ; Enquête rétrospective ; Evaluation risque Mots-clés : APPAREIL CIRCULATOIRE [PATHOLOGIE]  APPAREIL RESPIRATOIRE [PATHOLOGIE] Résumé : In the Air Pollution and Health: A European Approach (APHEA2) project, the effects of ambient ozone concentrations on mortality were investigated. Data were collected on daily ozone concentrations, the daily number of deaths, confounders, and potential effect modifiers from 23 cities/areas for at least 3 years since 1990. Effect estimates were obtained for each city with city-specific models and were combined using second-stage regression models. No significant effects were observed during the cold half of the year. For the warm season, an increase in the 1-hour ozone concentration by 10 mug/m3 was associated with a 0.33% (95% confidence interval [CI], 0.17-0.52) increase in the total daily number of deaths, 0.45% (95% CI, 0.22-0.69) in the number of cardiovascular deaths, and 1.13% (95% CI, 0.62-1.48) in the number of respiratory deaths. The corresponding figures for the 8-hour ozone were similar. The associations with total mortality were independent of SO2 and particulate matter with aerodynamic diameter less than 10 mum (PM10) but were somewhat confounded by NO2 and CO. Individual city estimates were heterogeneous for total (a higher standardized mortality rate was associated with larger effects) and cardiovascular mortality (larger effects were observed in southern cities). The dose-response curve of ozone effects on total mortality during the summer did not deviate significantly from linearity. PMID Pubmed : Pubmed : 15282198 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=5681 [article]

Air pollution attributable postneonatal infant mortality in U.S. metropolitan areas: a risk assessment study / Kaiser R in Environmental health [Environ Health], Vol. 3, N° 1 (05/2004)

[article]  inEnvironmental health [Environ Health] > Vol. 3, N° 1 (05/2004) . - p.4 Titre : Air pollution attributable postneonatal infant mortality in U.S. metropolitan areas: a risk assessment study Type de document : Article scientifique Auteur(s) : Kaiser R ; Romieu I ; Medina S ; Schwartz J ; Krzyzanowski M ; Kunzli N Appartenance auteur(s) InVS DSE Année de publication : 2004 Article en page(s) : p.4 Langues : Anglais (eng) Mots-clés : Pollution atmosphérique ; Mortalité ; Mort subite ; Nouveau né ; Particule atmosphérique ; Enquête cohorte ; Etats Unis ; Milieu urbain ; Evaluation risque Mots-clés : APPAREIL RESPIRATOIRE [PATHOLOGIE] Résumé : BACKGROUND: The impact of outdoor air pollution on infant mortality has not been quantified. METHODS: Based on exposure-response functions from a U.S. cohort study, we assessed the attributable risk of postneonatal infant mortality in 23 U.S. metropolitan areas related to particulate matter Lien externe DOI : DOI : 15128459 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=5656 [article]

Analysis of health outcome time series data in epidemiological studies / Touloumi G in Environmetrics, Vol. 15 (2004)

[article]  inEnvironmetrics > Vol. 15 (2004) . - 101-17 Titre : Analysis of health outcome time series data in epidemiological studies Type de document : Article scientifique Auteur(s) : Touloumi G ; Atkinson R ; Le Tertre A ; Samoli E ; Schwartz J ; Schindler C ; Vonk J ; Rossi G ; Saez M ; Rabczenko D ; Katsouyanni K Appartenance auteur(s) InVS DSE Année de publication : 2004 Article en page(s) : 101-17 Langues : Anglais (eng) Mots-clés : Statistique Mots-clés : SERIE TEMPORELLE Résumé : Several recent studies have reported significant health effects of air pollution even at low levels of air pollutants. These studies have been criticized for the statistical methods and for inconsistency in results between cities. An important development in air pollution epidemiology has come from multicenter studies. Within the APHEA-2 project we have developed a statistical methodology to evaluate short-term health effects of air pollution using data from 30 cities across Europe. For the analysis, a hierarchical modelling approach was adopted and implemented in two stages: (a) data from each city were analyzed separately to allow for local differences, using generalized additive Poisson regression models; (b) city-specific effects estimates were regressed on city-specific covariates to obtain an overall estimate and to explore heterogeneity across cities. In order to illustrate our methodology we present results for PM10 effects. It was found that a 10 microg/m3 increase in PM10 or NO2 concentrations is associated with a 0.67% (95% CI: 0.50 to 0.90) and 0.33% (0.20 to 0.40) increase in total mortality, respectively. After mutual adjustment, the PM10 effect was reduced by 40% and that of NO2 by 20%, but both pooled estimates remained significant. Long-term mean NO2 concentrations act as an effect modifier for PM10 effects, even after adjustment for NO2 confounding effects. In the second stage we explored two different models for combining the adjusted for NO2, PM10 effects across cities: bivariate, which accounts for within-city correlation of PM10 and NO2; and univariate, which ignores this correlation. Both models gave broadly the same results Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=5662 [article]

Apheis: public health impact of PM10 in 19 European cities / Medina S in Journal of epidemiology and community health [J Epidemiol Community Health], Vol. 58, N° 10 (10/2004)

[article]  inJournal of epidemiology and community health [J Epidemiol Community Health] > Vol. 58, N° 10 (10/2004) . - 831-6 Titre : Apheis: public health impact of PM10 in 19 European cities Type de document : Article scientifique Auteur(s) : Medina S ; Plasencia A ; Ballester F ; Mucke HG ; Schwartz J Appartenance auteur(s) InVS DSE Année de publication : 2004 Article en page(s) : 831-6 Langues : Anglais (eng) Mots-clés : Pollution atmosphérique ; Surveillance épidémiologique ; Europe ; Enquête épidémiologique ; Mortalité ; Particule atmosphérique ; Réseau surveillance ; Evaluation risque ; Milieu urbain ; Evaluation ; Mortalité prématurée Mots-clés : IMPACT Résumé : STUDY OBJECTIVE: Apheis is a public health surveillance system that aims to provide European, national, regional, and local decision makers, environmental health professionals, and the general public with up to date and easy to use information on air pollution and public health. This study presents the health impact assessment done in 19 cities of Western and Eastern European countries. DESIGN: Apheis developed guidelines for gathering and analysing data on air pollution and the impact on public health. Apheis has analysed the acute and chronic effects of fine particles on premature mortality using the estimates developed by Aphea2 study and two American cohort studies. This health impact assessment was performed for different scenarios on the health benefits of reducing levels of particles less than 10 microm in size (PM(10)). MAIN RESULTS: PM(10) concentrations were measured in 19 cities (range: 14-73 microg/m(3)). The population covered in this health impact assessment includes nearly 32 million inhabitants. The age standardised mortality rates (per 100 000 people) range from 456 in Toulouse to 1127 in Bucharest. Reducing long term exposure to PM(10) concentrations by 5 microg/m(3) would have "prevented" between 3300 and 7700 early deaths annually, 500 to 1000 of which are associated with short term exposure. CONCLUSIONS: Apheis shows that current levels of air pollution in urban Europe have a non-negligible impact on public health, and that preventive measures could reduce this impact, even in cities with low levels of air pollution. PMID Pubmed : Pubmed : 15365108 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=5668 [article]

Confounding and effect modification in the short-term effects of ambient particles on total mortality: results from 29 european cities within the APHEA2 Project / Katsouyanni K in Epidemiology, Vol. 12, N° 5 (09/2001)

[article]  inEpidemiology > Vol. 12, N° 5 (09/2001) . - 512-31 Titre : Confounding and effect modification in the short-term effects of ambient particles on total mortality: results from 29 european cities within the APHEA2 Project Type de document : Article scientifique Auteur(s) : Katsouyanni K ; Touloumi G ; Samoli E ; Gryparis A ; Le Tertre A ; Monopolis Y ; Rossi G ; Zmirou D ; Ballester F ; Boumghar A ; Anderson HR ; Wojtyniak B ; Paldy A ; Braunstein R ; Pekkanen J ; Schindler C ; Schwartz J Appartenance auteur(s) InVS DSE Année de publication : 2001 Article en page(s) : 512-31 Langues : Anglais (eng) Mots-clés : Pollution atmosphérique ; Europe ; Particule atmosphérique ; Fumée noire ; Ville ; Mortalité ; Réseau surveillance ; Surveillance épidémiologique Résumé : We present the results of the Air Pollution and Health: A European Approach 2 (APHEA2) project on short-term effects of ambient particles on mortality with emphasis on effect modification. We used daily measurements for particulate matter less than 10 um in aerodynamic diameter (PM10) and/or black smoke from 29 European cities. We considered confounding from other pollutants as well as meteorologic and chronologic variables. We investigated several variables describing the cities' pollution, climate, population, and geography as potential effect modifiers. For the individual city analysis, generalized additive models extending Poisson regression, using a smoother to control for seasonal patterns, were applied. To provide quantitative summaries of the results and explain remaining heterogeneity, we applied second-stage regression models. The estimated increase in the daily number of deaths for all ages for a 10 ug/m3 increase in daily PM10 or black smoke concentrations was 0.6% [95% confidence interval (CI) = 0.4-0.8%], whereas for the elderly it was slightly higher. We found important effect modification for several of the variables studied. Thus, in a city with low average NO2, the estimated increase in daily mortality for an increase of 10 ug/m3 in PM10 was 0.19 (95% CI = 0.00-0.41), whereas in a city with high average NO2 it was 0.80% (95% CI = 0.67-0.93%); in a relatively cold climate the corresponding effect was 0.29% (95% CI = 0.16-0.42), whereas in a warm climate it was 0.82% (95% CI = 0.69-0.96); in a city with low standardized mortality rate it was 0.80% (95% CI = 0.65-0.95%), and in one with a high rate it was 0.43% (95% CI = 0.24-0.62). Our results confirm those previously reported on the effects of ambient particles on mortality. Furthermore, they show that the heterogeneity found in the effect parameters among cities reflects real effect modification, which is explained by specific city characteristics. PMID Pubmed : Pubmed : 11505171 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=4169 [article]

Empirical bayes and adjusted estimates approach to estimating the relation of mortality to exposure of PM10 / Le Tertre A in Risk analysis [Risk Anal], Vol. 25, N° 3 (06/2005)

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Investigating the dose-response relation between air pollution and total mortality in the APHEA-2 multicity project / Samoli E in Occupational and environmental medicine [Occup Environ Med], Vol. 60, N° 12 (12/2003)

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Respiratory effects of sulphur dioxide: a hierarchical multicity analysis in the APHEA 2 study / Sunyer J in Occupational and environmental medicine [Occup Environ Med], Vol. 60, N° 8 (08/2003)

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Short-term effects of air pollution on total and cardiovascular mortality: the confounding effect of influenza epidemics / Touloumi G in Epidemiology, Vol. 16, N° 1 (2005)

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Short-term effects of ambient particles on mortality in the elderly: results from 28 cities in the APHEA2 project / Aga E in The European respiratory journal [Eur Respir J], Vol. 21, N° Suppl 40 (05/2003)

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Short-term effects of particulate air pollution on cardiovascular diseases in eight European cities / Le Tertre A in Journal of epidemiology and community health [J Epidemiol Community Health], Vol. 56, N° 10 (10/2002)

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The association of daily sulfur dioxide air pollution levels with hospital admissions for cardiovascular diseases in Europe (The Aphea-II study) / Sunyer J in European heart journal [Eur Heart J], Vol. 24, N° 8 (04/2003)

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The temporal pattern of mortality responses to ambient ozone in the APHEA project / Samoli E in Journal of epidemiology and community health [J Epidemiol Community Health], Vol. 63, N° 12 (12/2009)

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The temporal pattern of respiratory and heart disease mortality in response to air pollution / Zanobetti A in Environmental health perspectives [Environ Health Perspect], Vol. 111, N° 9 (07/2003)

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A time series study of drug sales and turbidity of tap water in Le Havre, France / Beaudeau P in Journal of water and health [J Water Health], Vol. 10, N°2 ([01/06/2012])

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