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Barriers to implementation of the new targeted BCG vaccination in France: A cross sectional study / Rossignol L in Vaccine, Vol. 29, N° 32 ([01/07/2011])

[article]  inVaccine > Vol. 29, N° 32 [01/07/2011] . - 5232-7 Titre : Barriers to implementation of the new targeted BCG vaccination in France: A cross sectional study Type de document : Article scientifique Auteur(s) : Rossignol L ; Guthmann JP ; Kerneis S ; Aubin Auger I ; Lasserre A ; Chauvin P ; Pelat C ; Hanslik T ; Levy Bruhl D ; Blanchon T Appartenance auteur(s) InVS DMI Mention d'édition : Vaccine Année de publication : 2011 Article en page(s) : 5232-7 Langues : Anglais (eng) Mots-clés : BCG ; Vaccination ; Médecin généraliste ; Enfant ; Enquête transversale ; Perception Résumé : The aim of the study was to assess factors influencing BCG vaccination among targeted children after the end of universal and mandatory BCG vaccination in France. A cross-sectional study was conducted in 2009 among general practitioners (GPs) of the French Sentinel Network. With the participation of 358 physician-investigators, 920 children were included. Of the 261 children (31%) identified to be at risk of tuberculosis, only 113 (44%) were vaccinated. The median number of French criteria for BCG vaccination correctly cited by the GPs was 3 of the existing 6. Of the 10 proposed, a median number of 5 regions in the world according to their level of tuberculosis risk were correctly classified by GPs. After adjustment using an alternating logistic model, 7 variables were found to be associated with the immunisation status of the target population. Six of these increased the probability of being vaccinated: children older than 6 months (OR=3.4 (CI 95% [1.4-8.6])), residents in central Paris or its suburbs (OR=14.7 [4.4-49.5]), children expected to travel to highly endemic regions (OR=3.5 [1.4-8.6]), those living in unfavourable conditions (OR=19.9 [6.2-63.9]), the GP's good knowledge of vaccination guidelines (OR=1.4 [1.1-1.9]) and the GP's perception of tuberculosis as a common disease (OR=2.2 [1.1-4.5]). Surprisingly, GPs with university training on infectious diseases tended to be more reluctant to follow vaccination guidelines (OR=0.14 [0.1-0.4]). Actions targeted at these factors could contribute to improving BCG immunisation coverage. (R.A.) PMID Pubmed : Pubmed : 21609744 Lien externe DOI : DOI : 10.1016/j.vaccine.2011.05.020 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=9627 [article]

Early estimates of 2009 pandemic influenza A(H1N1) virus activity in general practice in France. Incidence of influenza-like illness and age distribution of reported cases / Turbelin C in Eurosurveillance. European communicable disease monthly [Euro Surveill], Vol. 14, N° 39 (01/10/2009)  

[article]  inEurosurveillance. European communicable disease monthly [Euro Surveill] > Vol. 14, N° 39 (01/10/2009) . - pii=19341 Titre : Early estimates of 2009 pandemic influenza A(H1N1) virus activity in general practice in France. Incidence of influenza-like illness and age distribution of reported cases Type de document : Article scientifique Auteur(s) : Turbelin C ; Pelat C ; Boelle PY ; Levy Bruhl D ; Carrat F ; Blanchon T ; Hanslik T Appartenance auteur(s) InVS DMI Année de publication : 2009 Article en page(s) : pii=19341 Langues : Anglais (eng) Mots-clés : France ; Nouvelle grippe A (H1N1) ; Pandémie ; Incidence ; Situation épidémiologique ; Médecin généraliste Résumé : In the end of August 2009, an unusually elevated level of influenza-like illness (ILI) activity was reported to the French Sentinel Network. We quantified the observed excess in ILI cases in France during summer 2009 and characterised age patterns in reported cases. An excess of cases has been observed since 5 July, with a time increasing trend. The cumulated estimated excess number of ILI cases was 269,935 [179,585; 316,512], corresponding to 0.5% French population over the period. Compared to the same period in the past years, relative cumulated incidence was greater among young subjects and lower among subjects over 65 years old. Compared to past epidemics, the relative cumulated incidence was greater in children less than 5 years old. This excess of cases may reflect the current spread of the A(H1N1) virus in France, subject to the following limitations: estimates were based on clinical cases consulting a GP; large media coverage may have led to a non specific increase in consultation rates. PMID Pubmed : Pubmed : 19814965 Corpus : Grippe A(H1N1)/Production scientifique InVS Lien(s) externe(s) : http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19341 Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=8995 [article]

Documents numériques

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Field effectiveness of pandemic and 2009-2010 seasonal vaccines against 2009-2010 A(H1N1) influenza: estimations from surveillance data in France / Pelat C in PloS one [PLoS One], Vol. 6, N° 5 ([10/05/2011])  

[article]  inPloS one [PLoS One] > Vol. 6, N° 5 [10/05/2011] . - e19621 Titre : Field effectiveness of pandemic and 2009-2010 seasonal vaccines against 2009-2010 A(H1N1) influenza: estimations from surveillance data in France Type de document : Article scientifique Auteur(s) : Pelat C ; Falchi A ; Carrat F ; Mosnier A ; Bonmarin I ; Turbelin C ; Vaux S ; Van der Werf S ; Cohen JM ; Lina B ; Blanchon T ; Hanslik T Appartenance auteur(s) InVS DMI Année de publication : 2011 Article en page(s) : e19621 Langues : Anglais (eng) Mots-clés : Vaccin ; Vaccination ; Grippe ; Nouvelle grippe A (H1N1) ; Méthodologie ; France Résumé : Background: In this study, we assess how effective pandemic and trivalent 2009-2010 seasonal vaccines were in preventing influenza-like illness (ILI) during the 2009 A(H1N1) pandemic in France. We also compare vaccine effectiveness against ILI versus laboratory-confirmed pandemic A(H1N1) influenza, and assess the possible bias caused by using non-specific endpoints and observational data. Methodology and principal findings: we estimated vaccine effectiveness by using the following formula: VE = (PPV-PCV)/(PPV(1-PCV)) x 100%, where PPV is the proportion vaccinated in the population and PCV the proportion of vaccinated influenza cases. People were considered vaccinated three weeks after receiving a dose of vaccine. ILI and pandemic A(H1N1) laboratory-confirmed cases were obtained from two surveillance networks of general practitioners. During the epidemic, 99.7% of influenza isolates were pandemic A(H1N1). Pandemic and seasonal vaccine uptakes in the population were obtained from the National Health Insurance database and by telephonic surveys, respectively. Effectiveness estimates were adjusted by age and week. The presence of residual biases was explored by calculating vaccine effectiveness after the influenza period. The effectiveness of pandemic vaccines in preventing ILI was 52% (95% confidence interval: 30-69) during the pandemic and 33% (4-55) after. It was 86% (56-98) against confirmed influenza. The effectiveness of seasonal vaccines against ILI was 61% (56-66) during the pandemic and 19% (-10-41) after. It was 60% (41-74) against confirmed influenza. Conclusions: The effectiveness of pandemic vaccines in preventing confirmed pandemic A(H1N1) influenza on the field was high, consistently with published findings. It was significantly lower against ILI. This is unsurprising since not all ILI cases are caused by influenza. Trivalent 2009-2010 seasonal vaccines had a statistically significant effectiveness in preventing ILI and confirmed pandemic influenza, but were not better in preventing confirmed pandemic influenza than in preventing ILI. This lack of difference might be indicative of selection bias. PMID Pubmed : Pubmed : 21573005 Lien externe DOI : DOI : 10.1371/journal.pone.0019621 Corpus : Grippe A(H1N1)/Production scientifique InVS Lien(s) externe(s) : http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0019621 Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=9478 [article]

Documents numériques

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Herpes zoster : burden of disease in France / Gonzalez Chiappe S in Vaccine, Vol. 28, N° 50 (12/10/2010)

[article]  inVaccine > Vol. 28, N° 50 (12/10/2010) . - 7933-8 Titre : Herpes zoster : burden of disease in France Type de document : Article scientifique Auteur(s) : Gonzalez Chiappe S ; Sarazin M ; Turbelin C ; Lasserre A ; Pelat C ; Bonmarin I ; Chosidow O ; Blanchon T ; Hanslik T Appartenance auteur(s) InVS DMI Année de publication : 2010 Article en page(s) : 7933-8 Langues : Anglais (eng) Mots-clés : Zona ; Incidence ; Mortalité ; Hospitalisation ; France Résumé : This work provides estimates of HZ incidence and HZ-related hospitalization and mortality rates in France, where no immunization programme has been implemented. Herpes zoster data was obtained from the Sentinelles surveillance general practitioners (GPs) network, the PMSI Data processing centre for hospital discharges and from the French National Mortality Database (INSERM CépiDC). The yearly HZ incidence rate averaged 382 cases per 100,000 inhabitants (95% CI 364-405) and exponentially increased with age. The annual rates of hospitalizations and mortality due to HZ varied from 4.14+0.32 to 14.42+0.39 and from 0.11+0.03 to 0.29+0.04 per 100,000 inhabitants, respectively, depending on whether HZ was coded in a 'primary' or 'primary or associated' diagnosis. One or more factors of immunodepression occurred in 43.4% of hospitalized cases and in 21.6% HZ-related deaths. (R.A.) PMID Pubmed : Pubmed : 20946861 Lien externe DOI : DOI : 10.1016/j.vaccine.2010.09.074 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=519 [article]

Mumps. Burden of disease in France / Coffinieres E in Vaccine, Vol. 30, N° 49 ([19/11/2012])

[article]  inVaccine > Vol. 30, N° 49 [19/11/2012] . - 7013-8 Titre : Mumps. Burden of disease in France Type de document : Article scientifique Auteur(s) : Coffinieres E ; Turbelin C ; Riblier D ; Aouba A ; Levy Bruhl D ; Arena C ; Gonzalez Chiappe S ; Ferry JP ; Hanslik T ; Blanchon T Appartenance auteur(s) InVS DMI Année de publication : 2012 Article en page(s) : 7013-8 Langues : Anglais (eng) Mots-clés : Oreillons ; Hospitalisation ; Mortalité ; Incidence ; France Résumé : This article provides a review of the epidemiological data on mumps in France since 1986. The results of 26 years of monitoring in general practice by the Sentinel network are analysed, such as hospitalisation data between 2004 and 2010, as well as mortality data between 2000 and 2009. The annual incidence rate has plummeted between 1986 and 2011, from 859 cases per 100,000 inhabitants [95% CI: 798 920] to 9 cases per 100,000 inhabitants [95% CI: 4 14]. A change in the age distribution is significant with an increase of Relative Illness Ratio (RIR) for patients over 20 years. Since 2000, vaccine status has also changed, and the majority of recent mumps cases occur among previously vaccinated patients. The average annual hospitalisation rate is 3.2 per 1 million inhabitants. Mumps was identified as the initial cause of death in 1 case every 5 years. This study estimates the burden of mumps disease in France. (R.A.) Traduction du résumé : Cet article présente une revue des données épidémiologiques sur les oreillons en France depuis 1986. Les résultats de 26 années de suivi en médecine générale par le réseau Sentinelles sont analysés, ainsi que les données d'hospitalisation entre 2004 et 2010 et les données de mortalité entre 2000 et 2009. Le taux annuel d'incidence a chuté entre 1986 et 2011, passant de 859 cas pour 100 000 habitants [IC 95%: 798 - 920] à 9 cas pour 100 000 habitants [IC 95%: 4 - 14]. Un changement significatif dans la répartition par âge a été observé, avec une augmentation du ratio relatif de maladie (RRM) pour les patients de plus de 20 ans. Depuis 2000, le statut vaccinal a également évolué, la majorité des cas récents d'oreillons se produisant chez des patients vaccinés. Le taux annuel moyen d'hospitalisation est de 3,2 pour 1 million d'habitants. Les oreillons sont la cause initiale de décès dans 1 cas tous les 5 ans. Cette étude estime le poids de la maladie en France. (Traduction effectuée par la Cellule de Valorisation Editoriale - CeVE - de l'InVS) PMID Pubmed : Pubmed : 23059354 Lien externe DOI : DOI : 10.1016/j.vaccine.2012.09.070 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=11000 [article]

Nationwide surveillance of 18 respiratory viruses in patients with influenza-like illnesses: a pilot feasibility study in the French Sentinel Network / Falchi A in Journal of medical virology [J Med Virol], Vol. 83, N° 8 ([01/08/2011])

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Practices of French family physicians concerning varicella vaccination for teenagers / Blaizeau F in Médecine et maladies infectieuses [Med Mal Infect], Vol. 42, N° 9 ([01/09/2012])

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Prise en charge des troubles anxio-dépressifs chez le sujet âgé en médecine générale en France, 2007. Journées de veille sanitaire. Paris, 26, 27 et 28 novembre 2008 / Lasserre A 

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Prise en charge des troubles anxiodépressifs chez le sujet âgé en médecine générale en France. Congrès International d'Épidémiologie, Paris, 10-12 septembre 2008 / Lasserre A in Revue d'épidémiologie et de santé publique [Rev Epidemiol Sante Publique], Vol. 56, N° 5 suppl.1 (09/2008)

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Psychotropic drug use among older people in general practice: discrepancies between opinion and practice / Lasserre A in British Journal of General Practice [Br J Gen Pract], Vol. 60, N° 573 ([01/04/2010])

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Rates of immunization against pandemic and seasonal influenza in persons at high risk of severe influenza illness: a cross-sectional study among patients of the French Sentinelles general practitioners / Privileggio L in BMC Public Health [BMC Public Health], Vol. 13 ([20/03/2013]) 

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Simultaneous investigation of influenza and enteric viruses in the stools of adult patients consulting in general practice for acute diarrhea / Arena C in Virology Journal [Virol J], Vol. 9, N° 1 ([18/06/2012])

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A survey of primary care physician practices in antibiotic prescribing for the treatment of uncomplicated male gonoccocal urethritis / Falchi A in BMC family practice [BMC Fam Pract], Vol. 12, N° 1 (Mai 2011)

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The Chikungunya epidemic on La Réunion island in 2005–2006 : a cost-of-illness study / Soumahoro MK in PLoS neglected tropical diseases [PLoS Negl Trop Dis], 5(6): e1197 ([21/06/2011])

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