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Auteur Chikhi Brachet R
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Molecular epidemiology of caliciviruses detected in sporadic and outbreak cases of gastroenteritis in France from December 1998 to February 2004 / Bon F in Journal of clinical microbiology [J Clin Microbiol], Vol. 43, N° 9 (09/2005)
Titre : Molecular epidemiology of caliciviruses detected in sporadic and outbreak cases of gastroenteritis in France from December 1998 to February 2004 Type de document : Article scientifique Auteur(s) : Bon F ; Ambert Balay K ; Giraudon H ; Kaplon J ; Le Guyader S ; Pommepuy M ; Gallay A ; Vaillant V ; de Valk H ; Chikhi Brachet R ; Flahault A ; Pothier P ; Kohli E Appartenance auteur(s) InVS DMI Année de publication : 2005 Article en page(s) : 4659-64 Langues : Anglais (eng)
in Journal of clinical microbiology [J Clin Microbiol] > Vol. 43, N° 9 (09/2005) . - 4659-64
Mots-clés : Gastroentérite ; Surveillance épidémiologique ; Epidémie ; ADN ; Virus ; Age ; France ; Enquête épidémiologique Résumé : We compiled sequence and epidemiological data from 172 caliciviruses detected in France from December 1998 to February 2004 in sporadic and outbreak cases. The results showed a cocirculation of strains with a majority of genogroup II (GII) noroviruses. Three groups of noroviruses, not detected before in our laboratory, emerged and spread during the period: the recombinant GGIIb and Norwalk-related strains not amplified in the polymerase gene in 2000 and a new Lordsdale variant in 2002. We observed that (i) GII-4 noroviruses were predominant in nursing home and hospital outbreaks but rare in oyster- and water-related outbreaks despite continuous circulation in the population; (ii) at the opposite, genogroup I strains were detected in the majority of environmental outbreaks; (iii) several strains were frequently found in oyster- and water-linked outbreaks (up to seven), whereas one single strain was detected when transmission was from person to person; and (iv) whereas GII noroviruses were predominant in sporadic cases where patients were under 15 years of age, GI strains were more frequent in outbreaks occurring in this age group. Finally, from a methodology point of view, this compilation shows that detection and characterization in the polymerase gene are not adequate in a significant number of cases and should be completed by amplification and sequencing in the capsid gene. PMID Pubmed : Pubmed : 16145123 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=5335[article]Simultaneous investigation of influenza and enteric viruses in the stools of adult patients consulting in general practice for acute diarrhea / Arena C in Virology Journal [Virol J], Vol. 9, N° 1 ([18/06/2012])
Titre : Simultaneous investigation of influenza and enteric viruses in the stools of adult patients consulting in general practice for acute diarrhea Type de document : Article scientifique Auteur(s) : Arena C ; Amoros JP ; Vaillant V ; Balay K ; Chikhi Brachet R ; Varesi L ; Arrighi I ; Blanchon T ; Carrat F ; Hanslik T ; Falchi A Appartenance auteur(s) InVS DMI Année de publication : 2012 Article en page(s) : 116 Langues : Anglais (eng)
in Virology Journal [Virol J] > Vol. 9, N° 1 [18/06/2012] . - 116
Mots-clés : Adulte ; Entérovirus ; Influenza ; Excrétion ; Diarrhée Résumé : BACKGROUND: Gastrointestinal symptoms are not an uncommon manifestation of an influenza virusinfection. In the present study, we aimed to investigate the presence of influenza viruses inthe stools of adult patients consulting their general practitioner for uncomplicated acutediarrhea (AD) and the proportion of concurrent infections by enteric and influenza viruses.
METHOD: A case-control study was conducted from December 2010 to April 2011. Stool specimenswere collected and tested for influenza viruses A (seasonal A/H3N2 and pandemic A/H1N1)and B, and for four enteric viruses (astrovirus, group A rotavirus, human enteric adenovirus,norovirus of genogroups I - NoVGI - and genogroup II - NoVGII).
RESULTS: General practitioners enrolled 138 cases and 93 controls. Of the 138 stool specimenscollected, 92 (66.7%) were positive for at least one of the four enteric viruses analysed and 10(7.2%) tested positive for one influenza virus. None of these 10 influenza positive patientsreported respiratory symptoms. In five influenza-positive patients (3.6%), we also detectedone enteric virus, with 4 of them being positive for influenza B (2 had co-detection withNoVGI, 1 with NoVGII, and 1 with astrovirus). None of the 93 controls tested positive forone of the enteric and/or other influenza viruses we investigated.
CONCLUSIONS: In this study we showed that the simultaneous detection of influenza and enteric viruses is nota rare event. We have also reported, for the first time in general practice, the presence ofseasonal and pandemic influenza viruses in the stools of adult patients consulting foruncomplicated AD. A simultaneous investigation of enteric and influenza viruses in patientscomplaining of gastrointestinal symptoms could be useful for future studies to better identifythe agents responsible for AD.
PMID Pubmed : Pubmed : 22709374 Lien externe DOI : DOI : 10.1186/1743-422X-9-116 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=10802[article]