A partir de cette page vous pouvez :
| Retourner au premier écran avec les dernières notices... |
Détail de l'auteur
Auteur Eriksson M
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheOccupation and occupational exposure to endocrine disrupting chemicals in male breast cancer: a case control study in Europe / Villeneuve S in Occupational and environmental medicine [Occup Environ Med], Vol. 67, N°12 ([01/11/2010])
Titre : Occupation and occupational exposure to endocrine disrupting chemicals in male breast cancer: a case control study in Europe Type de document : Article scientifique Auteur(s) : Villeneuve S ; Cyr D ; Lynge E ; Orsi L ; Sabroe S ; Merletti F ; Gorini G ; Morales Suarez Varela M ; Ahrens W ; Baumgardt-Elms C ; Kaerlev L ; Eriksson M ; Hardell L ; Fevotte J ; Guenel P Appartenance auteur(s) InVS DST ; UMRESTTE Année de publication : 2010 Article en page(s) : 837-44 Langues : Anglais (eng)
in Occupational and environmental medicine [Occup Environ Med] > Vol. 67, N°12 [01/11/2010] . - 837-44Mots-clés : Cancer sein ; Homme ; Exposition professionnelle ; Produit chimique ; Incidence ; Industrie papier ; Industrie bois ; Industrie automobile ; Facteur risque ; Europe Résumé : Objectives. Male breast cancer is a rare disease of largely unknown aetiology. In addition to genetic and hormone-related risk factors, a large number of environmental chemicals are suspected of playing a role in breast cancer. The identification of occupations or occupational exposures associated with an increased incidence of breast cancer in men may help to identify mammary carcinogens in the environment. Methods Occupational risk factors for male breast cancer were investigated in a multi-centre case-control study conducted in eight European countries which included 104 cases and 1901 controls. Lifetime work history was obtained during in-person interviews. Occupational exposures to endocrine disrupting chemicals (alkylphenolic compounds, phthalates, polychlorinated biphenyls and dioxins) were assessed on a case-by-case basis using expert judgement. Results Male breast cancer incidence was particularly increased in motor vehicle mechanics (OR 2.1, 95% CI 1.0 to 4.4) with a dose-effect relationship with duration of employment. It was also increased in paper makers and painters, forestry and logging workers, health and social workers, and furniture manufacture workers. The OR for exposure to alkylphenolic compounds above the median was 3.8 (95% CI 1.5 to 9.5). This association persisted after adjustment for occupational exposures to other environmental oestrogens. Conclusion These findings suggest that some environmental chemicals are possible mammary carcinogens. Petrol, organic petroleum solvents or polycyclic aromatic hydrocarbons are suspect because of the consistent elevated risk of male breast cancer observed in motor vehicle mechanics. Endocrine disruptors such as alkylphenolic compounds may play a role in breast cancer. (R.A.) PMID Pubmed : Pubmed : 20798010 Lien externe DOI : DOI : 10.1136/oem.2009.052175 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=598 [article]
Titre : Occupational exposure to electromagnetic fields and sex-differential risk of uveal melanoma Type de document : Article scientifique Auteur(s) : Behrens T ; Lynge E ; Cree I ; Sabroe S ; Lutz JM ; Afonso N ; Eriksson M ; Guenel P ; Merletti F ; Morales Suarez Varela M ; Stengrevics A ; Fevotte J ; Llopis Gonzalez A ; Gorini G ; Sharkova G ; Hardell L ; Ahrens W Appartenance auteur(s) InVS DST ; UMRESTTE Année de publication : 2010 Article en page(s) : 751-9 Langues : Anglais (eng)
in Occupational and environmental medicine [Occup Environ Med] > Vol. 67, N°12 [01/11/2010] . - 751-9Mots-clés : Mélanome ; Rayonnement électromagnétique ; Exposition professionnelle ; Oeil ; Europe Résumé : Objectives. The association between occupational exposure to electromagnetic fields (EMF) and the risk of uveal melanoma was investigated in a case-control study in nine European countries. Methods. Incident cases of uveal melanoma and population as well as hospital controls were included and frequency matched by country, 5-year birth cohort and sex. Subjects were asked whether they had worked close to high-voltage electrical transmission installations, computer screens and various electrical machines, or in complex electrical environments. Measurements of two Scandinavian job-exposure matrices were applied to estimate lifelong cumulative EMF exposure. Unconditional logistic regression analyses, stratified by sex and eye colour were calculated, adjusting for several potential confounders. Results 293 patients with uveal melanoma and 3198 control subjects were interviewed. Women exposed to electrical transmission installations showed elevated risks (OR 5.81, 95% CI 1.72 to 19.66). Positive associations with exposure to control rooms were seen among men and women, but most risk increases were restricted to subjects with dark iris colour. Application of published EMF measurements revealed stronger risk increases among women compared to men. Again, elevated risks were restricted to subjects with dark eye colour. Conclusion. Although based on a low prevalence of exposure to potential occupational sources of EMF, our data indicate that exposed dark-eyed women may be at particular risk for uveal melanoma. (R.A.) PMID Pubmed : Pubmed : 20798011 Lien externe DOI : DOI : 10.1136/oem.2009.052225 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=601 [article]
Titre : Occupational exposure to endocrine-disrupting chemicals and the risk of uveal melanoma Type de document : Article scientifique Auteur(s) : Behrens T ; Lynge E ; Cree I ; Lutz JM ; Eriksson M ; Guenel P ; Merletti F ; Morales Suarez Varela M ; Afonso N ; Stengrevics A ; Stang A ; Fevotte J ; Sabroe S ; Llopis Gonzalez A ; Gorini G ; Hardell L ; Ahrens W Appartenance auteur(s) InVS DST ; UMRESTTE Année de publication : 2012 Article en page(s) : 476-83 Langues : Anglais (eng)
in Scandinavian journal of work, environment & health [Scand J Work Environ Health] > Vol. 38, N° 5 [01/09/2012] . - 476-83Mots-clés : Mélanome ; Oeil ; Exposition professionnelle ; Accident chimique ; Solvant ; Système endocrine Résumé : OBJECTIVES: We investigated the association between occupational exposure to endocrine-disrupting chemicals (EDC) and the risk of uveal melanoma using international data of a case-control study from nine European countries.
METHODS: After exclusion of proxy interviews, 280 cases and 3084 control subjects were included in the final analysis. Information on possible exposure to EDC was derived from 27 job-specific questionnaires (JSQ), which solicited detailed questions on occupational tasks. Relative risk estimates were based on the JSQ and potential exposure to a group of endocrine-disrupting agents. We constructed several exposure scores, taking into account intensity of exposure, use of personal protective equipment, and exposure duration. We calculated unconditional logistic regression analyses, adjusting for country, age, sex, eye color and a history of ocular damage due to intense ultraviolet (UV) exposure.
RESULTS: The overall exposure prevalence to EDC was low reaching a maximum of 11% for heavy metals with endocrine-disrupting properties. Although working in some industries was associated with increased melanoma risk [such as dry cleaning: odds ratio (OR) 6.15, 95% confidence interval (95% CI) 2.0-18.96 and working in the glass manufacturing industry: OR 3.49, 95% CI 1.10-11.10], agent-specific risks were not elevated. The strongest possible risk increase was observed for organic solvents with endocrine-disrupting properties (OR 1.31, 95% CI 0.78-2.21). Calculation of exposure scores did not indicate consistently elevated results with higher score values. Sensitivity analyses did not alter these results.
PMID Pubmed : Pubmed : 22179223 Lien externe DOI : DOI : 10.5271/sjweh.3265 Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=10256 [article]
Titre : Occupational exposure to organic solvents and risk of male breast cancer: a European multicenter case-control study Type de document : Article scientifique Auteur(s) : Laouali N ; Pilorget C ; Cyr D ; Neri M ; Kaerlev L ; Sabroe S ; Gorini G ; Richiardi L ; Morales Suarez Varela M ; Llopis Gonzalez A ; Ahrens W ; Jockel KH ; Afonso N ; Eriksson M ; Merletti E ; Olsen J ; Lynge E ; Guenel P Appartenance auteur(s) InVS DST Année de publication : 2018 Article en page(s) : 11 p. Langues : Anglais (eng)
in Scandinavian journal of work, environment & health [Scand J Work Environ Health] > In Press [06/02/2018] . - 11 p.Résumé : Objectives: the etiology of male breast cancer (MBC) is largely unknown but a causal role of exposure to organic solvents has been suggested. Previous studies on occupational risk factors of breast cancer were often restricted to women who are frequently exposed to lower levels and at a lower frequency than men. We investigated the association between MBC and occupational exposure to petroleum and oxygenated and chlorinated solvents in a multicenter case-control study of rare cancers in Europe.
Methods: the study included 104 MBC cases and 1901 controls. Detailed lifetime work history was obtained during interviews, together with sociodemographic characteristics, medical history and lifestyle factors. Occupational exposures to solvents were estimated from a job-exposure matrix. Odds ratios (OR) and their 95% confidence intervals (CI) were calculated using unconditional logistic regression models.
Results: lifetime cumulative exposure to trichloroethylene >23.9 ppm years was associated with an increased MBC risk, compared to non-exposure [OR (95% CI): 2.1 (1.2 4.0); P trend <0.01). This increase in risk persisted when only exposures that occurred ≥10 years before diagnosis were considered. In addition, a possible role for benzene and ethylene glycol in MBC risk was suggested, but no exposure-response trend was observed.
Conclusions: these findings add to the evidence of an increased risk of breast cancer among men professionally exposed to trichloroethylene and possibly to benzene or ethylene glycol. Further studies should be conducted in populations with high level of exposure to confirm our results.PMID Pubmed : Pubmed : 29405242 Lien externe DOI : DOI : 10.5271/sjweh.3717 Corpus : Santé publique France Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=13659 [article]
Titre : Pesticide exposure in farming and forestry and the risk of uveal melanoma Type de document : Article scientifique Auteur(s) : Behrens T ; Lynge E ; Cree I ; Lutz JM ; Eriksson M ; Guenel P ; Merletti F ; Morales Suarez Varela M ; Afonso N ; Stengrevics A ; Fevotte J ; Sabroe S ; Llopis Gonzalez A ; Gorini G ; Hardell L ; Stang A ; Ahrens W Appartenance auteur(s) InVS DST ; UMRESTTE Année de publication : 2012 Article en page(s) : 141-51 Langues : Anglais (eng)
in Cancer causes & control : CCC [Cancer Causes Control] > Vol. 23, N° 1 [01/01/2012] . - 141-51Mots-clés : Mélanome ; Oeil ; Pesticide ; Exposition professionnelle ; Exploitant agricole ; Agriculture ; Arboriculture ; Elevage ; Facteur risque ; Enquête cas témoin ; Europe Résumé : PURPOSE: Since pesticides are disputed risk factors for uveal melanoma, we studied the association between occupational pesticide exposure and uveal melanoma risk in a case-control study from nine European countries.
METHODS: Incident cases of uveal melanoma and population as well as hospital controls were included and frequency-matched by country, 5-year age groups and sex. Self-reported exposure was quantified with respect to duration of exposure and pesticide application method. We calculated the exposure intensity level based on application method and use of personal protective equipment. Odds ratios (OR) and 95% confidence intervals (95% CI) were estimated by unconditional logistic regression analyses and adjusted for several potential confounders.
RESULTS: 293 case and 3,198 control subjects were interviewed. We did not identify positive associations with activities in farming or forestry, pesticide application or pesticide mixing. No consistent positive associations were seen with exposure intensity level scores either. The only statistically significantly raised association in this study was for exposure to chemical fertilizers in forestry (OR = 8.93; 95% CI 1.73-42.13), but this observation was based on only six exposed subjects. Results did not change when we restricted analyses to morphologically verified cases and excluded proxy interviews as well as cancer controls. We did not observe effect modification by sex or eye color.
CONCLUSIONS: Risk estimates for pesticide exposures and occupational activities in agriculture and forestry were not increased and did not indicate a hormonal mechanism due to these exposures.
PMID Pubmed : Pubmed : 22052342 Lien externe DOI : DOI : 10.1007/s10552-011-9863-z Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=10048 [article]
