| Titre : | VEB-1 Extended-spectrum beta-lactamase-producing Acinetobacter baumannii, France |
| Type de document : | Article scientifique |
| Auteur(s) : | Naas T ; Coignard B ; Carbonne A ; Blanckaert K ; Bajolet Laudinat O ; Bernet C ; Verdeil X ; Astagneau P ; Desenclos JC ; Nordmann P |
| Appartenance auteur(s) InVS | DMI |
| Année de publication : | 2006 |
| Article en page(s) : | 1214-22 |
| Langues : | Anglais (eng) |
in Emerging infectious diseases [Emerg Infect Dis] > Vol. 12, N° 8 (08/2006) . - 1214-22| Mots-clés : | France ; Hôpital ; Epidémie ; Surinfection
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| Résumé : | VEB-1 extended-spectrum beta-lactamase-producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resist. |
| PMID Pubmed : | Pubmed : 16965700  |
| Corpus : | Production scientifique InVS |
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