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Biomarkers of exposure to environmental contaminants in French pregnant women from the Elfe cohort in 2011 / Dereumeaux C in Environment international [Environ Int], Vol. 97 ([01/10/2016])
Titre : Biomarkers of exposure to environmental contaminants in French pregnant women from the Elfe cohort in 2011 Type de document : Article scientifique Auteur(s) : Dereumeaux C ; Saoudi A ; Pecheux M ; Berat B ; de Crouy Chanel P ; Zaros C ; Brunel S ; Delamaire C ; Le Tertre A ; Lefranc A ; Vandentorren S ; Guldner L Appartenance auteur(s) InVS DSE Année de publication : 2016 Article en page(s) : 56-67 Langues : Anglais (eng)
in Environment international [Environ Int] > Vol. 97 [01/10/2016] . - 56-67
Mots-clés : Biosurveillance ; Perturbateur endocrinien ; Exposition environnementale ; Bisphénol A ; Phtalate ; Pesticide ; Dioxine ; Furane ; PCB ; Métal ; Femme enceinte ; Enquête cohorte ; France Résumé : Background: as part of the perinatal component of the French Human Biomonitoring (HBM) program, biomarkers levels of various chemicals have been described among pregnant women having given birth in continental France in 2011 and who have been enrolled in the Elfe cohort (French Longitudinal Study since Childhood). This paper describes the design of the study and provides main descriptive results regarding exposure biomarkers levels.
Methods: exposure biomarkers were measured in biological samples collected at delivery from pregnant women randomly selected among the participants in the clinical and biological component of the Elfe cohort (n = 4145). The geometric mean and percentiles of the levels distribution were estimated for each biomarker. The sampling design was taken into account in order to obtain estimates representative of the French pregnant women in 2011.
Results: results provide a nation-wide representative description of biomarker levels for important environmental contaminants among pregnant women who gave birth in France in 2011. Bisphenol A (BPA), and some metabolites of phthalates, pesticides (mainly pyrethroids), dioxins, furans, polychlorobiphenyls (PCBs), brominated flame retardants (BFRs), perfluorinated compounds (PFCs) and metals (except uranium) were quantified in almost 100% of the pregnant women. Some compounds showed a downward trend compared to previous studies (lead, mercury), but others did not (pyrethroids) and should be further monitored.
Conclusion and perspectives: the present results show that French pregnant women are exposed to a wide variety of pollutants, including some that have been banned or restricted in France.
PMID Pubmed : Pubmed : 27788374 Lien externe DOI : DOI : 10.1016/j.envint.2016.10.013 Corpus : Santé publique France Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=13171[article]Dioxins and furans in breast milk in France / Frery N in Organohalogen compounds [Organohalogen Compd], Vol. 48 ([01/01/2000])
Titre : Dioxins and furans in breast milk in France Type de document : Communication écrite-orale Auteur(s) : Frery N ; Deloraine A ; Dor F ; Zeghnoun A ; Rouviere F Appartenance auteur(s) InVS DSE ; 20th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2000) (13–17 August 2000; Monterey, CA, USA) Année de publication : 2000 Article en page(s) : 47-50 Langues : Anglais (eng)
in Organohalogen compounds [Organohalogen Compd] > Vol. 48 [01/01/2000] . - 47-50
Mots-clés : Dioxine ; Furane ; Lait maternel ; Carcinogène ; Biosurveillance ; France ; Dosage Corpus : Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=10319[article]The French Dioxin and Incinerators study: method of the study / Frery N in Organohalogen compounds [Organohalogen Compd], Vol. 69 ([01/01/2007])
Titre : The French Dioxin and Incinerators study: method of the study Type de document : Article scientifique Auteur(s) : Frery N ; Volatier JL ; Zeghnoun A ; Falq G ; Mouajjah S ; Thebault A ; Pascal M ; Berat B ; Grange D ; de Crouy Chanel P ; Sarter H ; Etchevers A ; Eppe G ; Heyman C ; Guillois Becel Y ; Lucas N ; Mathieu A ; Noury U ; Pouey J ; Schmitt M ; Le Strat Y ; Pelletier B ; Salines G ; DMI Appartenance auteur(s) InVS DSE ; Cire Nord ; Cire Ouest ; Cire Normandie ; Cire Midi-Pyrénées ; Cire Rhône-Alpes Année de publication : 2007 Article en page(s) : 2276-9 Langues : Anglais (eng)
in Organohalogen compounds [Organohalogen Compd] > Vol. 69 [01/01/2007] . - 2276-9
Mots-clés : Incinérateur ; Déchet ménager ; Dioxine ; Biosurveillance ; Furane ; Contamination aliment ; Biomarqueur ; Enquête épidémiologique ; Population générale ; France Résumé : The French Dioxin and Incinerators Study was carried out by the French Institute for Public Health Surveillance and the French Food Safety Agency in 8 different areas in France around municipal solid wastes incinerators. The population study was made up of adults who had been living for at least 10 years in the study area, not occupationally exposed to dioxins and for women with no breastfeeding. The individuals were selected through a random sampling and were provided 200 ml blood serum samples as well as their personal characteristics, eating habits, occupational and environmental exposure through a face to face interview. Exposure was assessed by serum concentrations of dioxins, furans and PCBs. The main goal of the study was to investigate whether living around incinerators was associated with elevated blood dioxins, furans and PCBs levels. To respond to this question, several statistical methods were used including univariate and multivariate analyses. All analyses were adjusted for survey sampling weights and used methods taken in to account the presence of non-detects. (R.A.) Corpus : CIRE/Production scientifique InVS Permalink : http://opac.invs.sante.fr/index.php?lvl=notice_display&id=9939[article]