| Résumé : | ABSTRACT: BACKGROUND: Evidence of a dose-response relationship between prenatal exposure to methylmercury (MeHg) and neurodevelopmental consequences in terms of IQ reduction, makes it possible to evaluate the economic consequences of MeHg exposures.
OBJECTIVE: To perform an economic evaluation of annual national benefits of reduction of the prenatal MeHg exposure in France.
METHODS: We used data on hair-Hg concentrations in French women of childbearing age (18-45 years) from a national sample of 126 women and from two studies conducted in coastal regions (n = 161and n = 503). A linear dose response function with a slope of 0.465 IQ point reduction per mug/g increase in hair-Hg concentration was used, along with a log transformation of the exposure scale, where a doubling of exposure was associated with a loss of 1.5 IQ points. The costs calculations utilized an updated estimate of E2008 17,363 per IQ point decrement, with three hypothetical exposure cut-off points (hair-Hg of 0.58, 1.0, and 2.5 mug/g).
RESULTS: Because of higher exposure levels of women in coastal communities, the annual economic impacts based on these data were greater than those using the national data, i.e. E 1.62 billion (national), and E 3.02 billion and E 2.51 billion (regional), respectively, with the linear model, and E 5.46 billion (national), and E 9.13 billion and E 8.17 billion (regional), with the log model, for exposures above 0.58 mug/g.
CONCLUSIONS: These results emphasize that efforts to reduce MeHg exposures would have high social benefits by preventing the serious and lifelong consequences of neurodevelopmental deficits in children. (R.A.)
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Ajouter le résultat dans votre panier Affiner la rechercheCognitive, visual, and motor development of 7-month-old Guadeloupean infants exposed to chlordecone / Dallaire R in Environmental research [Environ Res], Vol. 118 ([01/10/2012])
Effets du méthylmercure sur la santé / Saviuc P
ELFE (Étude Longitudinale Française depuis l'Enfance). Mise en place d'une cohorte nationale de 20 000 enfants. Congrès d'épidémiologie Adelf / Epiter. Dijon, 30-31 août et 1er septembre 2006 / Vandentorren S
