| Résumé : | In April 2005, an outbreak of Chikungunya fever occurred on the island of Reunion in the Indian Ocean. During winter 2005, six patients developed meningoencephalitis and acute hepatitis due to Chikungunya virus. Our objectives were to determine the incidence and mortality of atypical Chikungunya viral infections and to identify risk factors for severe disease. A hospital-based surveillance system was established to collect data on atypical Chikungunya cases. Case reports, medical records and laboratory results were reviewed and analysed. We defined an atypical case as one in which a patient with laboratory-confirmed Chikungunya virus infection developed symptoms other than fever and arthralgia. We defined a severe atypical case as one which required maintenance of at least one vital function. We recorded 610 atypical cases of Chikungunya fever: 222 were severe cases, 65 affected patients died. Five hundred and forty-six cases had underlying medical conditions (of which 226 suffered from cardiovascular, 147 from neurological and 150 from respiratory disorders). Clinical features that had never been associated with Chikungunya fever were recorded, such as bullous dermatosis, pneumonia, and diabetes mellitus. Hypertension, and underlying respiratory or cardiological conditions were independent risk factors for disease severity. The overall mortality rate was 10.6% and it increased with age. This is the first time that severe cases and deaths due to Chikungunya fever have been documented. The information presented in this article may assist clinicians in identifying the disease, selecting the treatment strategy, and anticipating the course of illness. (R.A.) |
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Océan Indien
Ajouter le résultat dans votre panier Affiner la recherche5 ans de chikungunya à la Réunion : point épidémiologique. 1ère Journée régionale de veille sanitaire de la Réunion. 7 décembre 2010 / Renault P
Analyse exploratoire visant à identifier les facteurs de gravité des accidents de la vie courante, Île de La Réunion, France. Données de l’étude Epac, 2005-2009 / Giron S in Bulletin Epidémiologique Hebdomadaire [Bull Epidemiol Hebd], N° 7 ([01/03/2011])
Les cas de paludisme répondant aux critères de la déclaration obligatoire, de 2001 à 2003. Surveillance nationale des maladies infectieuses, 2001-2003 / Jeannel D
